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Papers of the Week


Papers: 25 Mar 2023 - 31 Mar 2023

RESEARCH TYPE:
Basic Science, Psychology


Animal Studies, Medical Devices, Molecular/Cellular, Neurobiology, Neuromodulation

PAIN TYPE:
Neuropathic Pain, Psychological/Comorbidities


2023 Mar


Pain Physician


36988364


26


2

Spinal Interferon Regulatory Factor 8 and Brain-derived Neurotrophic Factor in the Prefrontal Cortex are Involved in Pain-induced Depression Relief via Ultrasound-guided Pulsed Radiofrequency in a Rat Spared Nerve Injury Model.

Authors

Lyu C, Zhou J, Wu Q, Fang X

Abstract

Pain-depression comorbidity has become a great burden to individuals and society. Nevertheless, the mechanisms underlying comorbid diseases have still not been fully revealed. Ultrasound-guided pulsed radiofrequency (PRF) on peripheral nerves, which produces remarkable analgesia via high-frequency electromagnetic energy, has become a main, minimally invasive treatment for chronic neuropathic pain.