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Papers of the Week


Papers: 1 Feb 2025 - 7 Feb 2025


2025 Feb 03


J Headache Pain


39901101


26


1

Shift from chronic to episodic migraine frequency in a long-term phase 3 study of galcanezumab.

Authors

Diener HC, Day KA, Lipsius S, Aurora SK, Hindiyeh NA, Detke HC

Abstract

Chronic migraine (CM) is a highly disabling form of migraine in which patients have ≥ 15 headache days per month, of which at least 8 have the features of migraine. Galcanezumab is a monoclonal antibody to calcitonin gene-related peptide which is approved for the preventive treatment of migraine. Ability to convert patients from chronic migraine frequency to episodic migraine (EM) frequency is a clinically relevant and desirable outcome when prescribing preventive treatments to patients with CM.