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Papers of the Week


Papers: 1 Mar 2025 - 7 Mar 2025


2025


Front Endocrinol (Lausanne)


40046872


16

Shared diagnostic biomarkers and underlying mechanisms between endometriosis and recurrent implantation failure.

Authors

Li H, Zhu C, Gu Y, Wei X, Wang X, Yang X, Zhang H

Abstract

Endometriosis (EMs) is a common condition that causes dysmenorrhea, chronic pelvic pain, and infertility, affecting millions of women worldwide. Despite the use of assisted reproductive technology, EMs patients often experience lower embryo implantation rates and recurrent implantation failure (RIF) due to impaired uterine endometrial receptivity. This study aims to identify shared diagnostic genes and underlying mechanisms between EMs and RIF using integrated transcriptomic analysis and machine learning with Gene Expression Omnibus (GEO) datasets.