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Papers of the Week


Papers: 15 Jul 2023 - 21 Jul 2023

RESEARCH TYPE:
Clinical


Human Studies, Neurobiology, Neuroimaging, Sex Differences

PAIN TYPE:
Neuropathic Pain, Orofacial/Head Pain


2023 Jul 12


Neurol Sci


37436558

Sex differences in trigeminal neuralgia: a focus on radiological and clinical characteristics.

Authors

De Stefano G, Litewczuk D, Mollica C, Di Pietro G, Galosi E, Leone C, Falco P, Tullo MG, Caramia F, Truini A, Di Stefano G

Abstract

It is well established that trigeminal neuralgia is more prevalent in females than in males. Neurovascular compression with morphological changes of the trigeminal root represents the most recognized etiological factor. However, other factors may play a role in the framework of a multi-hit model. The primary aim of this study was to investigate sex differences in radiological and clinical characteristics of trigeminal neuralgia to better understand the multifactorial origin of this peculiar neuropathic pain condition.