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Papers of the Week
Sex differences in the biomechanical and biochemical responses of caudal rat intervertebral discs to injury.
Authors
Kenawy HM, Nuñez MI, Morales X, Lisiewski LE, Burt KG, Kim MKM, Campos L, Kiridly N, Hung CT, Chahine NOAbstract
Intervertebral disc degeneration (IDD) is a major cause of low back pain (LBP) worldwide. Sexual dimorphism, or sex-based differences, appear to exist in the severity of LBP. However, it is unknown if there are sex-based differences in the inflammatory, biomechanical, biochemical, and histological responses of intervertebral discs (IVDs).