Serine protease inhibitor E2 protects against cartilage tissue destruction and inflammation in osteoarthritis by targeting NF-κB signaling.
Authors
Wang L, Chen S, Zhang H, Wei G, Ma F, Zhang M, Zhang B, Yang S, Cheng H, Yang R, Wang R, Liu M, Song Y, Li X, E X
Abstract
Osteoarthritis (OA) is a chronic disease characterized by cartilage degeneration and inflammation, with no approved disease-modifying drugs. This study aimed to identify pathogenic genes and elucidate their mechanism in OA.
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