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Papers of the Week


Papers: 20 May 2023 - 26 May 2023

RESEARCH TYPE:
Clinical


Human Studies, Neurobiology, Pharmacology/Drug Development

PAIN TYPE:
Migraine/Headache


2023 Jun


Lancet Neurol


37210098


22


6

Safety and efficacy of rimegepant orally disintegrating tablet for the acute treatment of migraine in China and South Korea: a phase 3, double-blind, randomised, placebo-controlled trial.

Authors

Yu S, Kim BK, Guo A, Kim MH, Zhang M, Wang Z, Liu J, Moon HS, Tan G, Yang Q, McGrath D, Hanna M, Stock DA, Gao Y, Croop R, Lu Z

Abstract

No acute treatments targeting calcitonin gene-related peptide (CGRP) have been approved for use in China or South Korea. We aimed to compare the efficacy and safety of rimegepant-an orally administered small molecule CGRP antagonist-with placebo in the acute treatment of migraine among adults in these countries.