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Papers of the Week


Papers: 1 Feb 2025 - 7 Feb 2025


2025 Feb 06


Reg Anesth Pain Med


39915245

Role of spinal Barrier-to-Autointegration Factor (BAF) in the epigenetic silencing of the mu-opioid receptor gene in neuropathic pain.

Authors

Hsieh MC, Lai CY, Lin TB, Wang HH, Cheng JK, Yang PS, Hsu CC, Chou D, Peng HY

Abstract

Neuropathic pain presents a significant clinical challenge, with spinal cord epigenetic mechanisms playing a critical role in its development. This study investigated the impact of nerve injury on the Barrier-to-Autointegration Factor (BAF) in the rat spinal dorsal horn.