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Papers of the Week

Papers: 25 Nov 2023 - 1 Dec 2023

2023 Nov 25

Lipids Health Dis




Role of arachidonic acid metabolism in intervertebral disc degeneration: identification of potential biomarkers and therapeutic targets via multi-omics analysis and artificial intelligence strategies.


Tan J, Shi M, Li B, Liu Y, Luo S, Cheng X


Intervertebral disc degeneration (IVDD) is widely recognized as the primary etiological factor underlying low back pain, often necessitating surgical intervention as the sole recourse in severe cases. The metabolic pathway of arachidonic acid (AA), a pivotal regulator of inflammatory responses, influences the development and progression of IVDD.