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Papers of the Week


Papers: 11 Mar 2023 - 17 Mar 2023

RESEARCH TYPE:
Basic Science


Animal Studies, Neurobiology, Pharmacology/Drug Development

PAIN TYPE:
Inflammation/Inflammatory, Migraine/Headache


2023


Front Neurol


36908624


14

Rodent behavior following a dural inflammation model with anti-CGRP migraine medication treatment.

Authors

Reducha PV, Bömers JP, Edvinsson L, Haanes KA

Abstract

Migraine is a widespread and prevalent disease with a complex pathophysiology, of which neuroinflammation and increased pain sensitivity have been suggested to be involved. Various studies have investigated the presence of different inflammatory markers in migraineurs and investigated the role of inflammation in inflammatory models with complete Freund’s adjuvant (CFA) or inflammatory soup added to the dura mater.