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Papers of the Week
RNA-binding protein SYNCRIP contributes to neuropathic pain through stabilising CCR2 expression in primary sensory neurones.
Authors
Zhang Y, Wang B, Feng X, Wang H, Gao J, Li X, Huo X, Yasin B, Bekker A, Hu H, Tao YXAbstract
Nerve injury-induced changes in gene expression in the dorsal root ganglion (DRG) contribute to the genesis of neuropathic pain. SYNCRIP, an RNA-binding protein, is critical for the stabilisation of gene expression. Whether SYNCRIP participates in nerve injury-induced alterations in DRG gene expression and nociceptive hypersensitivity is unknown.