I am a
Home I AM A Search Login

Papers of the Week

Papers: 15 Jul 2023 - 21 Jul 2023

Clinical, Pediatric, Psychology, Sex/Gender/Race

Human Studies, Neurobiology, Sex Differences


2023 Jul 06

Clin J Pain


Risk Factors for the Development of Multisite Pain in Children.


Kaplan CM, Schrepf A, Boehnke KF, He Y, Smith T, Williams DA, Bergmans R, Voepel-Lewis T, Hassett AL, Harris RE, Clauw DJ, Beltz AM, Harte SE


Chronic pain has economic costs on par with cardiovascular disease, diabetes, and cancer. Despite this impact on the health care system and an increasing awareness of the relationship between pain and mortality, efforts to identify simple symptom-based risk factors for the development of pain, particularly in children, have fallen short. This is critically important as pain that manifests during childhood often persists into adulthood. To date no longitudinal studies have examined symptoms in pain-free children that presage a new, multisite manifestation of pain in the future. We hypothesized that female sex, sleep problems and heightened somatic complaints at baseline would be associated with the risk of developing new multisite pain one year later.