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Papers of the Week
Reward system neurodynamics during menstrual pain modulated by COMTVal158Met polymorphisms.
Authors
Hsu PS, Liu CH, Yang CJ, Lee LC, Li WC, Chao HT, Lin MW, Chen LF, Hsieh JCAbstract
Primary dysmenorrhea (PDM), characterized by cyclic pain, may involve pain modulation within the reward system (RS). The Catechol-O-methyltransferase () Val158Met polymorphism, which significantly influences dopamine activity, is linked to the regulation of both acute and chronic pain. This study examines the differential neurodynamic modulation in the RS associated with Val158Met polymorphisms during menstrual pain among PDM subjects.