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Papers of the Week

Papers: 20 Jan 2024 - 26 Jan 2024

2024 Jan 24

Br J Anaesth


Rethinking ketamine as a panacea: adverse effects on oxygenation and postoperative outcomes.


Rolfzen ML, Palanca BJA, Bartels K


Ketamine is receiving renewed interest in perioperative medicine as an anaesthetic adjunct and a treatment for chronic conditions, including depression. Ketamine’s complex pharmacologic profile results not only in several desirable effects, such as anaesthesia and analgesia, but also multiple adverse effects affecting the central nervous, cardiovascular, and respiratory systems. In addition to defining patient-centred outcomes in future clinical studies on the perioperative uses of ketamine, careful monitoring for its numerous adverse effects will be paramount.