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Papers of the Week
Resistant and refractory migraine – two different entities with different comorbidities? Results from the REFINE study.
Authors
Rosignoli C, Ornello R, Caponnetto V, Onofri A, Avaltroni S, Braschinsky M, Šved O, Gil-Gouveia R, Lampl C, Paungarttner J, Martelletti P, Wells-Gatnik WD, Martins IP, Mitsikostas D, Apostolakopoulou L, Nabaei G, Ozge A, Narin DB, Pozo-Rosich P, Muñoz-Vendrell A, Prudenzano MP, Gentile M, Ryliskiene K, Vainauskiene J, Del Rio MS, Vernieri F, Iaccarino G, Waliszewska-Prosol M, Budrewicz S, Carnovali M, Katsarava Z, Sacco SAbstract
Resistant and refractory migraine are commonly encountered in specialized headache centers. Several comorbidities, mostly psychiatric conditions, have been linked to migraine worsening; however, there is little knowledge of the comorbidity profile of individuals with resistant and refractory migraine.