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Papers of the Week
Research Progress on the Experimental Model and Underlying Mechanistic Studies of Tension-Type Headaches.
Authors
Fu GJ, Wang LD, Chi XS, Liang X, Wei JJ, Huang ZH, Shen W, Zhang YLAbstract
Tension-type headaches (TTH) significantly diminish patients’ quality of life and increase absenteeism, thereby imposing a substantial economic burden. Animal models are essential tools for studying disease mechanisms and drug development. However, until now, little focus has been placed on summarizing the animal models of TTH and associated mechanistic studies. This narrative review discusses the current animal models of TTH and related mechanistic studies to provide insights into the pathophysiological mechanisms of and treatments for TTH.