Reactive astrocytes mediate postoperative surgery-induced anxiety through modulation of GABAergic signalling in the zona incerta of mice.
Authors
Tong K, Song YT, Jing SQ, You Y, Wang SJ, Wu T, Xu H, Zhang JW, Liu L, Hao JR, Sun N, Cao JL, Gao C
Abstract
Surgery can induce severe neuroinflammation and negative emotional symptoms, such as anxiety-like behaviour. We studied whether reactive astrocytes in the zona incerta (ZI) mediate surgery-induced anxiety in mice.
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