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Papers of the Week


Papers: 23 Nov 2024 - 29 Nov 2024


2024 Nov 25


Br J Anaesth


39592364

Reactive astrocytes mediate postoperative surgery-induced anxiety through modulation of GABAergic signalling in the zona incerta of mice.

Authors

Tong K, Song YT, Jing SQ, You Y, Wang SJ, Wu T, Xu H, Zhang JW, Liu L, Hao JR, Sun N, Cao JL, Gao C

Abstract

Surgery can induce severe neuroinflammation and negative emotional symptoms, such as anxiety-like behaviour. We studied whether reactive astrocytes in the zona incerta (ZI) mediate surgery-induced anxiety in mice.