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Papers of the Week


Papers: 2 Sep 2023 - 8 Sep 2023

RESEARCH TYPE:
Basic Science


Animal Studies, Neurobiology

PAIN TYPE:
Migraine/Headache, Psychological/Comorbidities


2023 Sep 05


J Headache Pain


37667199


24


1

Proteomics profiling reveals mitochondrial damage in the thalamus in a mouse model of chronic migraine.

Authors

Xie W, Li R, Tang W, Ma Z, Miao S, Li C, Yang C, Li B, Wang T, Gong Z, Zhou Y, Yu S

Abstract

Migraine, a complex brain disorder, is regarded as a possible clinical manifestation of brain energy dysfunction. The trigeminovascular system is considered the basis for the pathogenesis of migraine, hence we depicted the proteomics profiling of key regions in this system, then focusing on protein alterations related to mitochondrial function. The aim of this study is to illustrate the role of mitochondria in migraine.