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Papers of the Week


Papers: 25 Mar 2023 - 31 Mar 2023

RESEARCH TYPE:
Basic Science


Animal Studies, Molecular/Cellular, Neurobiology

PAIN TYPE:
Neuropathic Pain


2023


J Pain Res


36968761


16

Proteomic Analysis of the Spinal Dorsal Horn in Mice with Neuropathic Pain After Exercise.

Authors

Bai J, Zhang J, Zhou L, Hua Y

Abstract

Neuropathic pain (NP) is a chronic pain state with a complex etiology that currently lacks effective treatment in clinical practice. Studies have found that exercise training can alleviate NP hyperalgesia, but the specific mechanism remains unclear. Here, we sought to identify proteins and signaling pathways critical for mediating the effects of treadmill training on NP in a mouse model of spared nerve injury (SNI).