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Papers of the Week

Papers: 23 Mar 2024 - 29 Mar 2024

2024 Mar 25

J Transl Med




Protective effect of synbiotic combination of Lactobacillus plantarum SC-5 and olive oil extract tyrosol in a murine model of ulcerative colitis.


Yu F, Hu X, Ren H, Wang X, Shi R, Guo J, Chang J, Zhou X, Jin Y, Li Y, Liu Z, Hu P


Ulcerative colitisis (UC) classified as a form of inflammatory bowel diseases (IBD) characterized by chronic, nonspecific, and recurrent symptoms with a poor prognosis. Common clinical manifestations of UC include diarrhea, fecal bleeding, and abdominal pain. Even though anti-inflammatory drugs can help alleviate symptoms of IBD, their long-term use is limited due to potential side effects. Therefore, alternative approaches for the treatment and prevention of inflammation in UC are crucial.