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Papers of the Week

Papers: 1 Jun 2024 - 7 Jun 2024

2024 Jun 03

Biol Psychiatry


Presynaptic and postsynaptic mesolimbic dopamine D receptors play distinct roles in cocaine versus opioid reward in mice.


Xi ZX, Bocarsly ME, Galaj E, Hempel B, Teresi C, Shaw M, Bi GH, Jordan C, Linz E, Alton H, Tanda G, Freyberg Z, Alvarez VA, Newman AH


Past research illuminated pivotal roles of dopamine D receptors (D3Rs) in the rewarding effects of cocaine and opioids. However, the cellular and neural circuit mechanisms underlying these actions remain unclear.