Presynaptic and postsynaptic mesolimbic dopamine D receptors play distinct roles in cocaine versus opioid reward in mice.
Authors
Xi ZX, Bocarsly ME, Galaj E, Hempel B, Teresi C, Shaw M, Bi GH, Jordan C, Linz E, Alton H, Tanda G, Freyberg Z, Alvarez VA, Newman AH
Abstract
Past research illuminated pivotal roles of dopamine D receptors (D3Rs) in the rewarding effects of cocaine and opioids. However, the cellular and neural circuit mechanisms underlying these actions remain unclear.
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