Pregabalin produces analgesia in males but not females in an animal model of chronic widespread muscle pain.
Authors
Plumb AN, Hayashi K, Janowski A, Smith A, Rasmussen L, Sluka KA, Lesnak JB
Abstract
Pregabalin, which acts on the αδ-1 subunit of voltage-gated calcium channels, relieves ≥50% of pain in a third of individuals with fibromyalgia. Thus far, preclinical studies of pregabalin have predominantly used male animals.
This website or its third-party tools use cookies, which are necessary to its functioning and required to achieve the purposes illustrated in the cookie policy. If you want to know more or withdraw your consent to all or some of the cookies, please refer to the IASP Privacy Policy. By closing this banner, you agree to the use of cookies.Agree
