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Papers of the Week
Platelet-rich plasma alleviates neuropathic pain in osteoarthritis by downregulating microglial activation.
Authors
Yan X, Ye Y, Wang L, Xue J, Shen N, Li TAbstract
The development of neuropathic pain (NP) is one of the reasons why the pain is difficult to treat, and microglial activation plays an important role in NP. Recently, platelet-rich plasma (PRP) has emerged as a novel therapeutic method for knee osteoarthritis (KOA). However, it’s unclarified whether PRP has analgesic effects on NP induced by KOA and the underlying mechanisms unknown.