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Papers of the Week


Papers: 6 May 2023 - 12 May 2023

RESEARCH TYPE:
Basic Science


Human Studies, Molecular/Cellular, Neurobiology

PAIN TYPE:
Migraine/Headache


2023


Front Neurol


37143998


14

Plasma levels of VIP are not elevated during PACAP- and VIP-induced cluster headache attacks: an exploratory study.

Authors

Deligianni C, Pellesi L, Chaudhry BA, Haulund Vollesen AL, Snoer AH, Hannibal J, Jensen RH, Ashina M

Abstract

Pituitary adenylate cyclase-activating peptide (PACAP) and vasoactive intestinal peptide (VIP) provoked cluster headache attacks in individuals with episodic cluster headache during their active phase and individuals with chronic cluster headache. In this study, we investigated whether infusions of PACAP and VIP caused alterations in plasma levels of VIP and their potential contribution to induced cluster headache attacks.