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Papers: 4 Mar 2023 - 10 Mar 2023
RESEARCH TYPE:
Basic Science
Animal Studies, Genetics, Neurobiology
PAIN TYPE:
Neuropathic Pain
2023 Mar 03
Anesthesiology
Nonsense-mediated mRNA decay increases targeted mRNA degradation and has been implicated in the regulation of gene expression in neurons. We hypothesized that nonsense-mediated μ opioid receptor mRNA decay in the spinal cord is involved in the development of neuropathic allodynia-like behavior in rats.