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Papers of the Week


Papers: 1 Mar 2025 - 7 Mar 2025


2025 Feb 27


Oral Dis


40013649

Pathogenesis of Orofacial Pain Based on Brain Circuits.

Authors

Nagamine T

Abstract

Orofacial pain is comprised of three distinct components: sensory, perception, and experience or memory. Each of these components is associated with its own specific brain circuit, thereby classifying orofacial pain into three distinct circuits: “peripheral pain,” “brain network pain,” and “memorized pain.” Individuals afflicted with chronic orofacial pain of unknown etiology exhibit characteristics indicative of both brain network pain and memorized pain, necessitating a biopsychosocial approach that takes into account psychosocial factors in addition to the sensory aspects of pain.