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Papers of the Week


Papers: 3 Jun 2023 - 9 Jun 2023

RESEARCH TYPE:
Basic Science


Genetics, In Vitro Studies, Molecular/Cellular

PAIN TYPE:
Arthritis, Inflammation/Inflammatory


2023 Jun 02


Comb Chem High Throughput Screen


37264620

Over-expression of microRNA-145 elevating autophagy activities via downregulating FRS2 expression.

Authors

Ke T, Bin D, Xiaodong H, Haiyi Z, Tao L, Wang Z, Yuanmin Z, Guodong W

Abstract

Osteoarthritis (OA) is one of the most common chronic and progressive joint diseases characterized by cartilage degeneration and chondrocyte death. In this study, we aimed to identify the modulation effect of miR-145 on chondrocytes’ autophagy during the development of OA.