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Papers of the Week


Papers: 17 Aug 2024 - 23 Aug 2024


2024 Aug


CNS Neurosci Ther


39169794


30


8

OTULIN’s influence on neuroinflammation and pain modulation in trigeminal neuralgia.

Authors

Wang H, Wang H, Zheng W, Wang D, Sun C, Dong J, Yu W, Du Q

Abstract

Trigeminal neuralgia (TN), marked by chronic pain from neural damage, is closely associated with inflammation. The role of OTULIN, a key regulator in inflammation and autophagy, is not fully understood in TN. The regulatory mechanism of OTULIN, a key protein involved in modulating inflammatory responses and autophagy processes, remains incompletely elucidated, particularly in the context of TN and neuroinflammation.