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Papers of the Week

Papers: 10 Feb 2024 - 16 Feb 2024


J Pain Res



Optimizing Temporal Summation of Heat Pain Using a Constant Contact Heat Stimulator.


Kell PA, Vore CN, Hahn BJ, Payne MF, Rhudy JL


Temporal summation (TS) of pain occurs when pain increases over repeated presentations of identical noxious stimuli. TS paradigms can model central sensitization, a state of hyperexcitability in nociceptive pathways that promotes chronic pain onset and maintenance. Many experimenters use painful heat stimuli to measure TS (TS-heat); yet, TS-heat research faces unresolved challenges, including difficulty evoking summation in up to 30-50% of participants. Moreover, substantial variability exists between laboratories regarding the methods for evoking and calculating TS-heat.