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Papers of the Week
Ononin delays the development of osteoarthritis by down-regulating MAPK and NF-κB pathways in rat models.
Authors
Xu F, Li Z, Jiang Y, Liao T, Aschner M, Wei QAbstract
Osteoarthritis (OA) is featured as cartilage loss, joint pain and loss of labor, which the inflammatory reaction may play critical roles. Ononin is an isoflavone isolating from medicinal plants and has anti-inflammatory effects. Our study investigated the anti-inflammation response of ononin on OA.