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Papers of the Week


Papers: 15 Apr 2023 - 21 Apr 2023

RESEARCH TYPE:
Basic Science


Animal Studies, Molecular/Cellular, Neurobiology

PAIN TYPE:
Arthritis, Inflammation/Inflammatory


2023 Apr 15


Arthritis Res Ther


37061736


25


1

Notch signaling is activated in knee-innervating dorsal root ganglia in experimental models of osteoarthritis joint pain.

Authors

Wang L, Ishihara S, Li J, Miller RE, Malfait AM

Abstract

We aimed to explore activation of the Notch signaling pathway in knee-innervating lumbar dorsal root ganglia (DRG) in the course of experimental osteoarthritis (OA) in mice, and its role in knee hyperalgesia.