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Papers of the Week
Noradrenergic Locus Coeruleus-CA3 Activation Alleviates Neuropathic Pain and Anxiety- and Depression-Like Behaviors by Suppressing Microglial Neuroinflammation in SNI Mice.
Authors
Zou H, Pu W, Zhou J, Li J, Ma L, Wang S, Liu C, Mou J, Liu X, Yu T, Wei Y, Xie H, Cao SAbstract
Neuropathic pain (NP) arises from neuroimmune interactions following nerve injury and is often accompanied by anxiety and depression. The aim of the study is to evaluate the effects of the noradrenergic locus coeruleus (LC), a key regulator of pain and emotional states, projects extensively to the hippocampus.