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Papers of the Week
Non-invasive Central Nervous System Assessment of A Porcine Model of Neuropathic Pain Demonstrates Increased Latency of Somatosensory-evoked Potentials.
Authors
Hilgart DR, Iversen MM, Peters AY, Zabriskie MS, Hoareau GL, Vapniarsky N, Clark GA, Shah LM, Rieke VAbstract
The study of chronic pain and its treatments requires a robust animal model with objective and quantifiable metrics. Porcine neuropathic pain models have been assessed with peripheral pain recordings and behavioral responses, but thus far central nervous system electrophysiology has not been investigated. This work aimed to record non-invasive, somatosensory-evoked potentials (SEPs) via electroencephalography in order to quantitatively assess chronic neuropathic pain induced in a porcine model.