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Papers of the Week
NGF-releasing Prussian blue nanoparticles for nerve injury repair of lumbar disc herniation.
Authors
Tang X, Sun X, Ji Y, Huang X, Xiao S, Zhou Y, Ma K, Yuan HAbstract
Compression of the nerve root by a lumbar disc herniation can cause radiating pain in the lower limbs, and the nerve root decompression treatment may leave some patients with motor dysfunction and reduced sensory function. Studies have shown that nerve growth factor (NGF) can promote nerve growth and repair, but high doses, long duration, and immune response have become bottlenecks of its clinical application.