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Papers of the Week


Papers: 4 Mar 2023 - 10 Mar 2023

RESEARCH TYPE:
Review


Molecular/Cellular

PAIN TYPE:
Cancer Pain, Neuropathic Pain


2023 Mar 02


EBioMedicine


36870200


90

Neutrophil extracellular traps as a unique target in the treatment of chemotherapy-induced peripheral neuropathy.

Authors

Wang CY, Lin TT, Hu L, Xu CJ, Hu F, Wan L, Yang X, Wu XF, Zhang XT, Li Y, Yin HY, Jiang CY, Xin HL, Liu WT

Abstract

Chemotherapy-induced peripheral neuropathy (CIPN) is a severe dose-limiting side effect of chemotherapy and remains a huge clinical challenge. Here, we explore the role of microcirculation hypoxia induced by neutrophil extracellular traps (NETs) in the development of CIPN and look for potential treatment.