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Papers of the Week

Papers: 3 Feb 2024 - 9 Feb 2024

2024 Feb 07

Mol Biol Rep




Neuropathic pain development following nerve injury is mediated by SOX11-ARID1A-SOCS3 transcriptional regulation in the spinal cord.


Le D, Zhang C, Liu L, Zhao M, Liang Y, Liao P, Yang F


Neuropathic pain, a complex condition originating from nervous system damage, remains a significant clinical challenge due to limited understanding of its underlying mechanisms. Recent research highlights the SOX11 transcription factor, known for its role in nervous system development, as a crucial player in neuropathic pain development and maintenance. This study investigates the role of the SOX11-ARID1A-SOCS3 pathway in neuropathic pain modulation within the spinal cord.