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Papers of the Week


Papers: 22 Feb 2025 - 28 Feb 2025


2025 Mar


Brain Behav Immun Health


40008232


44

Neuroimmunology of psoriasis: Possible roles for calcitonin gene-related peptide in its pathogenesis.

Authors

Kotlyar J, Granstein RD

Abstract

The nervous system has a complex interplay with the immune system, especially at barrier sites such as the skin. This allows it to play a role in a variety of cutaneous inflammatory disorders such as psoriasis, exerting effects on various immune cells via effector molecules such as neuropeptides. In this review, we discuss the role of calcitonin gene-related peptide in modulating the immune system and inflammation, with a focus on psoriasis.