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Papers of the Week
MR thermometry imaging for low intensity focused ultrasound modulation of spinal nervous tissue.
Authors
Olinger C, Vest J, Tarasek M, Yeo D, DiMarzio M, Burdette C, Williams E, Khazen O, Pilitsis JGAbstract
Previously in rodent and swine models, we have shown that external low intensity focused ultrasound (liFUS) can be used to modulate pain responses. To ensure no adverse heating events occur with liFUS modulation in a non-invasive manner, we perform initial work in swine to show that magnetic resonance thermometry imaging (MRTI) is capable of measuring <2.0 °C changes at the L5 DRG. Further, we show that our device can be constructed in an MR-compatible fashion to minimize artifact.