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Papers of the Week

Papers: 5 Aug 2023 - 11 Aug 2023

Basic Science

Genetics, Human Studies, Molecular/Cellular, Neurobiology

Acute Pain, Psychological/Comorbidities

2023 Aug 04

Mol Pain


Mitochondrial Reactivity Following Acute Exposure to Experimental Pain Testing in People with HIV and Chronic Pain.


Gilstrap SR, Hobson JM, Owens MA, White DM, Sammy MJ, Ballinger SW, Sorge RE, Goodin B


Physical stressors can cause a physiological response that can contribute to an increase in mitochondrial dysfunction and mtDNA damage. People living with HIV (PWH) are more likely to suffer from chronic pain and may be more susceptible to mitochondrial dysfunction following exposure to a stressor. We used Quantitative Sensory Testing (QST) as an acute painful stressor in order to investigate whether PWH with/without chronic pain show differential mitochondrial physiological responses.