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Papers of the Week


Papers: 19 Oct 2024 - 25 Oct 2024


2024 Dec


Pain Rep


39430682


9


6

miR-374 family is a key regulator of chronic primary pain onset.

Authors

Hernandez NP, Rawls A, Chen J, Zhang X, Wang Y, Gao X, Parisien M, Karaky M, Meloto CB, Montagna F, Dang H, Pan Y, Zhao Y, McLean S, Linnstaedt S, Diatchenko L, Nackley AG

Abstract

Chronic primary pain conditions (CPPCs) are linked to catecholamine activation of peripheral adrenergic receptors. Yet, catecholamine-dependent epigenetic mechanisms, such as microRNA (miRNA) regulation of mRNA transcripts, remain largely unknown.