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Papers: 18 Mar 2023 - 24 Mar 2023
RESEARCH TYPE:
Basic Science
Animal Studies, Molecular/Cellular, Neurobiology, Neuroimaging
2023 Mar 21
J Neuroinflammation
20
1
Long-term smoking is a risk factor for chronic pain, and chronic nicotine exposure induces pain-like effects in rodents. The anterior cingulate cortex (ACC) has been demonstrated to be associated with pain and substance abuse. This study aims to investigate whether ACC microglia are altered in response to chronic nicotine exposure and their interaction with ACC neurons and subsequent nicotine-induced allodynia in mice.