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Papers of the Week


Papers: 17 Jun 2023 - 23 Jun 2023

RESEARCH TYPE:
Basic Science


Pharmacology/Drug Development

PAIN TYPE:
Arthritis, Inflammation/Inflammatory


2023 Jun 10


Colloids Surf B Biointerfaces


37348266


228

Meloxicam emulgel potently suppressed cartilage degradation in knee osteoarthritis: Optimization, formulation, industrial scalability and pharmacodynamic analysis.

Authors

Jyothi VGS, Veerabomma H, Kumar R, Khatri DK, Singh SB, Madan J

Abstract

Meloxicam (MLX) is prescribed for the management of pain and inflammation allied with osteoarthritis (OA). However, MLX causes intestinal damage in long term administration. Hence, meloxicam loaded emulgel (MLX-emulgel) was optimized, formulated and examined under stringent parameters in monosodium-iodoacetate (MIA) induced knee OA in Wistar rats.