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Papers of the Week

Papers: 10 Feb 2024 - 16 Feb 2024

2024 Feb 14

Br J Anaesth


Melatonin treatment has consistent but transient beneficial effects on sleep measures and pain in patients with severe chronic pain: the DREAM-CP randomised controlled trial.


Onyeakazi UM, Columb MO, Rosalind A, Kanakarajan S, Galley HF


Sleep disturbance is a major issue for patients with chronic pain. Melatonin has been shown to improve symptoms of fibromyalgia, but its efficacy in other chronic non-malignant pain conditions is not fully known. Hence, we determined the effect of melatonin in patients with severe noncancer chronic pain.