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Papers of the Week
Managing the neuroinflammatory pain of endometriosis in light of chronic pelvic pain.
Authors
Pergolizzi JV, LeQuang JA, Coluzzi F, El-Tallawy SN, Magnusson P, Ahmed RS, Varrassi G, Porpora MGAbstract
Endometriosis affects 5% to 10% of reproductive age women and may be associated with severely painful and debilitating symptoms as well as infertility. Endometriosis involves hormonal fluctuations, angiogenesis, neurogenesis, vascular changes and neuroinflammatory processes. The neuroinflammatory component of endometriosis makes it a systemic disorder, similar to other chronic epithelial inflammatory conditions.