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Papers of the Week


Papers: 22 Mar 2025 - 28 Mar 2025


2025 Mar 21


J Diabetes Investig


40116696

Machine learning-based risk prediction model for neuropathic foot ulcers in patients with diabetic peripheral neuropathy.

Authors

Shi G, Gao Z, Zhang Z, Jin Q, Li S, Liu J, Kou L, Aerman A, Yang W, Wang Q, Cai F, Zhang L

Abstract

Diabetic peripheral neuropathy (DPN) is a common chronic complication of diabetes, marked by symptoms like hyperalgesia, numbness, and swelling that impair quality of life. Nerve conduction abnormalities in DPN significantly increase the risk of neuropathic foot ulcers (NFU), which can progress rapidly and lead to severe outcomes, including infection, gangrene, and amputation. Early prediction of NFU in DPN patients is crucial for timely intervention.