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Papers of the Week
Long-term efficacy and reduced side-effects of buprenorphine in patients with moderate and severe chronic pain.
Authors
Papa A, Salzano AM, Di Dato MT, Desiderio V, Buonavolontà P, Mango P, Saracco E, Tammaro D, Luongo L, Maione SAbstract
Chronic pain significantly impacts quality of life and poses substantial public health challenges. Buprenorphine, a synthetic analog of thebaine, is recognized for its potential in managing moderate to severe chronic pain with fewer side effects and a lower incidence of tolerance compared to traditional opioids.