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Papers of the Week

Papers: 2 Mar 2024 - 7 Mar 2024

2024 Mar 05

Mod Rheumatol


LncRNA OIP5-AS1 promotes mitophagy to alleviate osteoarthritis by up-regulating PPAR-γ to activate AMPK/Akt/mTOR pathway.


Sun Z, Tang J, You T, Zhang B, Liu Y, Liu J


Osteoarthritis (OA) is the most common chronic joint degenerative disease. Mitophagy is closely related to OA pathogenesis. Herein, we investigated the role of lncRNA OIP5-AS1 in regulating mitophagy during OA.