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Papers of the Week

Papers: 8 Jun 2024 - 14 Jun 2024

2024 Mar 13

J Dermatol Sci


LEKTI domain 6 displays anti-inflammatory action in vitro and in a murine atopic dermatitis model.


Canbolat P, Wilzopolski J, Kaessmeyer S, Filor V, Vidak J, Rüger M, Mägert HJ, Forssmann WG, Bäumer W


Lympho-epithelial Kazal-type-related inhibitor (LEKTI) is a serine protease inhibitor consisting of multiple domains. A loss of function mutation is described in Netherton patients that show severe symptoms of atopic lesions and itch.