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Papers of the Week


Papers: 25 Mar 2023 - 31 Mar 2023

RESEARCH TYPE:
Review


Human Studies

PAIN TYPE:
Itch


2023 Mar 23


Psychosom Med


36961347

Learned nocebo effects on cutaneous sensations of pain and itch: A systematic review and meta-analysis of experimental behavioral studies on healthy humans.

Authors

Thomaidou MA, Blythe JS, Peerdeman KJ, van Laarhoven AIM, Van Schothorst MME, Veldhuijzen DS, Evers AWM

Abstract

In past decades, the field of nocebo research has focused on studying how sensory perception can be shaped by learning. Nocebo effects refer to aggravated sensory experiences or increased sensitivity to sensations such as pain and itch resulting from treatment-related negative experiences. Behavioral conditioning as well as verbal suggestions of a negative treatment outcome may aggravate pain and itch perception. Gaining a comprehensive view of the magnitude of nocebo effects and contributing factors will help steer nocebo research towards fruitful directions for understanding complex sensory phenomena.